Donor Peripheral Stem Cell Transplant in Treating Patients With Relapsed Acute Myeloid Leukemia

PHASE2CompletedINTERVENTIONAL
Enrollment

21

Participants

Timeline

Start Date

March 31, 2005

Primary Completion Date

June 30, 2008

Study Completion Date

June 30, 2008

Conditions
Leukemia
Interventions
BIOLOGICAL

aldesleukin

10 million units three times a week for a total of 6 doses. For any subject less than 45 kilograms the IL-2 will be given at 5 million units per meter squared three times weekly for a total of 6 doses

BIOLOGICAL

therapeutic allogeneic lymphocytes

Cells infused per kg. 1.5-8.0 x 10\^7/kg Total cells infused(for 70 kg. adult) 1.05 - 5.6 x 10\^9

DRUG

cyclophosphamide

Days -5 and -4: 60 mg/kg

DRUG

fludarabine phosphate

Days -5 through -2: 25 mg/m\^2

PROCEDURE

in vitro treated peripheral blood stem cell transplantation

Day 0 infuse natural killer cells

Trial Locations (1)

55455

Masonic Cancer Center, Minneapolis

All Listed Sponsors
lead

Masonic Cancer Center, University of Minnesota

OTHER

NCT00274846 - Donor Peripheral Stem Cell Transplant in Treating Patients With Relapsed Acute Myeloid Leukemia | Biotech Hunter | Biotech Hunter