207
Participants
Start Date
June 30, 2006
Primary Completion Date
September 30, 2010
Study Completion Date
March 31, 2013
Cognitive Behavioral Therapy
Behavioral therapy includes standard cognitive behavioral therapy, with an emphasis on behavioral activation. Treatment is administered on the basis of the participants' individual needs and may continue for up to 12 months.
Motivational Interviewing
Motivational interviewing is designed to address alcohol and drug use.
FDA-Approved Anti-Anxiety Medications
Participants assigned to receive the combination therapy may receive one or more of the following medications based on their individual needs: fluoxetine, sertraline, paroxetine, buspirone, propranolol, trazodone, and any of the benzodiazepines. Participants may begin receiving medication immediately or anytime within the 12 months post-injury. Form, dosage, frequency, and duration depend on patient need, but all are prescribed in accordance with standards of care.
Standard Care Control
Standard care control includes the usual treatment for injured trauma survivors.
Harborview Medical Center, Seattle
National Institute of Mental Health (NIMH)
NIH
University of Washington
OTHER