TY800 Dose Escalation (Typhoid)

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

47

Participants

Timeline

Start Date

February 28, 2006

Primary Completion Date

January 31, 2007

Study Completion Date

January 31, 2007

Conditions
Typhoid and Paratyphoid Fevers
Interventions
BIOLOGICAL

Ty800

Live attenuated Ty800 S typhi oral vaccine is co-administered with a sodium bicarbonate buffer solution. Dosages: 5 X 10\^7 cfu, 5 X 10\^8 cfu, and 5 X 10\^9 cfu.

DRUG

Placebo

150 mL of the prepared sodium bicarbonate buffer solution. Placebo will look and taste essentially like the study product.

Trial Locations (1)

45229

Cincinnati Children's Hospital Medical Center, Cincinnati

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00269295 - TY800 Dose Escalation (Typhoid) | Biotech Hunter | Biotech Hunter