A Study of Safety and Effectiveness of Ustekinumab (CNTO 1275) in Patients With Moderate to Severe Plaque-type Psoriasis

PHASE3CompletedINTERVENTIONAL
Enrollment

766

Participants

Timeline

Start Date

December 31, 2005

Primary Completion Date

July 31, 2006

Study Completion Date

May 31, 2011

Conditions
Psoriasis
Interventions
DRUG

ustekinumab

Type = exact number, Form = solution for injection, Number = 45 and 90, Unit = mg, Route = subcutaneous (SC) administered at Weeks 0, 4 and 16. Both treatments (45 mg and 90 mg) administered every 12 weeks after Week 16 depending on clinical response.

DRUG

placebo

Form = solution for injection, route = SC administered at Weeks 0 and 4. At Weeks 12 and 16, placebo will be crossed over to receive ustekinumab 45 mg or 90 mg.

Trial Locations (42)

Unknown

Phoenix

Los Angeles

Redwood City

Santa Monica

Denver

Wilmington

Ocala

Alpharetta

Marietta

Newnan

Honolulu

Boise

Normal

Indianapolis

Lake Charles

Worcester

Fridley

St Louis

Omaha

East Windsor

Albuquerque

New York

Lake Oswego

Portland

Goodlettsville

Dallas

Seattle

Milwaukee

Brussels

Edegem

Edmonton

Moncton

St. John's

Halifax

London

North Bay

Toronto

Waterloo

Windsor

Montreal

Sainte-Foy

Sherbrooke

All Listed Sponsors
lead

Centocor Research & Development, Inc.

INDUSTRY

NCT00267969 - A Study of Safety and Effectiveness of Ustekinumab (CNTO 1275) in Patients With Moderate to Severe Plaque-type Psoriasis | Biotech Hunter | Biotech Hunter