NCT00267748View on ClinicalTrials.gov

Sunitinib Malate Schedule 4/2 vs. Sunitinib Malate Continuous Dosing As First-Line Therapy For Metastatic Renal Cell Cancer (RCC)

PHASE2CompletedINTERVENTIONAL
Enrollment

317

Participants

Timeline

Start Date

December 31, 2005

Primary Completion Date

June 30, 2010

Study Completion Date

June 30, 2010

Conditions
Carcinoma, Renal Cell
Interventions
DRUG

Sunitinib Malate Continuous Daily Dosing

Sunitinib malate starting dose 37.5 mg daily continuous daily regimen.

DRUG

Sunitinib Malate Schedule 4/2

Sunitinib malate starting dose 50 mg per day for four weeks, followed by a two week off-drug period. This six week cycle is repeated.

Trial Locations (156)

10021

Pfizer Investigational Site, New York

10022

Pfizer Investigational Site, New York

10032

Pfizer Investigational Site, New York

12010

Pfizer Investigational Site, Amsterdam

12110

Pfizer Investigational Site, Latham

12148

Pfizer Investigational Site, Rexford

12180

Pfizer Investigational Site, Troy

12206

Pfizer Investigational Site, Albany

12208

Pfizer Investigational Site, Albany

12534

Pfizer Investigational Site, Hudson

14420

Pfizer Investigational Site, Brockport

14424

Pfizer Investigational Site, Canadaigua

14456

Pfizer Investigational Site, Geneva

14623

Pfizer Investigational Site, Rochester

14626

Pfizer Investigational Site, Rochester

18508

Pfizer Investigational Site, Scranton

19713

Pfizer Investigational Site, Newark

19718

Pfizer Investigational Site, Newark

19899

Pfizer Investigational Site, Wilmington

20817

Pfizer Investigational Site, Bethesda

21201

Pfizer Investigational Site, Baltimore

21237

Pfizer Investigational Site, Baltimore

23188

Pfizer Investigational Site, Williamsburg

23320

Pfizer Investigational Site, Chesapeake

23456

Pfizer Investigational Site, Virginia Beach

23502

Pfizer Investigational Site, Newport News

Pfizer Investigational Site, Norfolk

23601

Pfizer Investigational Site, Newport News

23666

Pfizer Investigational Site, Hampton

26506

Pfizer Investigational Site, Morgantown

27518

Pfizer Investigational Site, Cary

27534

Pfizer Investigational Site, Goldsboro

27607

Pfizer Investigational Site, Raleigh

27614

Pfizer Investigational Site, Raleigh

27893

Pfizer Investigational Site, Wilson

27909

Pfizer Investigational Site, Elizabeth City

28328

Pfizer Investigational Site, Clinton

28602

Pfizer Investigational Site, Hickory

29307

Pfizer Investigational Site, Spartanburg

29605

Pfizer Investigational Site, Greenville

29615

Pfizer Investigational Site, Greenville

29640

Pfizer Investigational Site, Easley

29672

Pfizer Investigational Site, Seneca

31902

Pfizer Investigational Site, Columbus

31904

Pfizer Investigational Site, Columbus

32806

Pfizer Investigational Site, Orlando

33484

Pfizer Investigational Site, Delray Beach

33486

Pfizer Investigational Site, Boca Raton

33805

Pfizer Investigational Site, Lakeland

40065

Pfizer Investigational Site, Shelbyville

40202

Pfizer Investigational Site, Louisville

40207

Pfizer Investigational Site, Louisville

40217

Pfizer Investigational Site, Louisville

40536

Pfizer Investigational Site, Lexington

43219

Pfizer Investigational Site, Columbus

44718

Pfizer Investigational Site, Canton

46350

Pfizer Investigational Site, La Porte

46360

Pfizer Investigational Site, Michigan City

46514

Pfizer Investigational Site, Elkhart

46563

Pfizer Investigational Site, Plymouth

46601

Pfizer Investigational Site, South Bend

46617

Pfizer Investigational Site, South Bend

47130

Pfizer Investigational Site, Jefferson

49085

Pfizer Investigational Site, Saint Joseph

49120

Pfizer Investigational Site, Niles

49424

Pfizer Investigational Site, Holland

49503

Pfizer Investigational Site, Grand Rapids

52402

Pfizer Investigational Site, Cedar Rapids

53792

Pfizer Investigational Site, Madison

63090

Pfizer Investigational Site, Washington

63141

Pfizer Investigational Site, St Louis

70006

Pfizer Investigational Site, Metairie

70056

Pfizer Investigational Site, Gretna

70072

Pfizer Investigational Site, Marrero

70115

Pfizer Investigational Site, New Orleans

70433

Pfizer Investigational Site, Covington

70809

Pfizer Investigational Site, Baton Rouge

71103

Pfizer Investigational Site, Shreveport

71913

Pfizer Investigational Site, Hot Springs

72205

Pfizer Investigational Site, Little Rock

73071

Pfizer Investigational Site, Norman

73102

Pfizer Investigational Site, Oklahoma City

73109

Pfizer Investigational Site, Oklahoma City

73120

Pfizer Investigational Site, Oklahoma City

74104

Pfizer Investigational Site, Tulsa

74133

Pfizer Investigational Site, Tulsa

75230

Pfizer Investigational Site, Dallas

75246

Pfizer Investigational Site, Dallas

75702

Pfizer Investigational Site, Tyler

76022

Pfizer Investigational Site, Bedford

76177

Pfizer Investigational Site, Fort Worth

77598

Pfizer Investigational Site, Webster

78207

Pfizer Investigational Site, San Antonio

78217

Pfizer Investigational Site, San Antonio

78229

Pfizer Investigational Site, San Antonio

78258

Pfizer Investigational Site, San Antonio

78463

Pfizer Investigational Site, Corpus Christi

78626

Pfizer Investigational Site, Georgetown

78681

Pfizer Investigational Site, Round Rock

78705

Pfizer Investigational Site, Austin

78731

Pfizer Investigational Site, Austin

78745

Pfizer Investigational Site, Austin

78758

Pfizer Investigational Site, Austin

78759

Pfizer Investigational Site, Austin

80012

Pfizer Investigational Site, Aurora

80120

Pfizer Investigational Site, Littleton

80124

Pfizer Investigational Site, Lone Tree

80138

Pfizer Investigational Site, Parker

80218

Pfizer Investigational Site, Denver

80220

Pfizer Investigational Site, Denver

80228

Pfizer Investigational Site, Lakewood

80260

Pfizer Investigational Site, Thorton

80303

Pfizer Investigational Site, Boulder

80304

Pfizer Investigational Site, Boulder

80501

Pfizer Investigational Site, Longmont

80909

Pfizer Investigational Site, Colorado Springs

81008

Pfizer Investigational Site, Pueblo

83712

Pfizer Investigational Site, Boise

84112

Pfizer Investigational Site, Salt Lake City

89052

Pfizer Investigational Site, Henderson

89128

Pfizer Investigational Site, Las Vegas

89135

Pfizer Investigational Site, Las Vegas

89148

Pfizer Investigational Site, Las Vegas

89169

Pfizer Investigational Site, Las Vegas

90027

Pfizer Investigational Site, Los Angeles

90034

Pfizer Investigational Site, Los Angeles

90095

Pfizer Investigational Site, Los Angeles

90706

Pfizer Investigational Site, Bellflower

91010

Pfizer Investigational Site, Duarte

91365

Pfizer Investigational Site, Woodland Hills

91402

Pfizer Investigational Site, Panorama City

91706

Pfizer Investigational Site, Baldwin Park

92108

Pfizer Investigational Site, San Diego

92120

Pfizer Investigational Site, San Diego

92335

Pfizer Investigational Site, Fontana

92505

Pfizer Investigational Site, Riverside

92618

Pfizer Investigational Site, Irvine

92807

Pfizer Investigational Site, Anaheim

97401

Pfizer Investigational Site, Eugene

97477

Pfizer Investigational Site, Springfield

98109

Pfizer Investigational Site, Seattle

98195

Pfizer Investigational Site, Seattle

06360

Pfizer Investigational Site, Norwich

46902-3803

Pfizer Investigational Site, Kokomo

46350-5533

Pfizer Investigational Site, La Porte

40536-0293

Pfizer Investigational Site, Lexington

49085-2112

Pfizer Investigational Site, Saint Joseph

49085-2158

Pfizer Investigational Site, Saint Joseph

07601

Pfizer Investigational Site, Hackensack

87131-0001

Pfizer Investigational Site, Albuquerque

87401-5631

Pfizer Investigational Site, Farmington

73112-4416

Pfizer Investigational Site, Oklahoma City

74136-1902

Pfizer Investigational Site, Tulsa

18512-3169

Pfizer Investigational Site, Dunmore

17043-1440

Pfizer Investigational Site, Lemoyne

19111-2497

Pfizer Investigational Site, Philadelphia

Sponsors

Lead Sponsor

Pfizer
All Listed Sponsors
lead

Pfizer

INDUSTRY