49
Participants
Start Date
December 31, 2005
Primary Completion Date
July 31, 2009
Study Completion Date
July 31, 2009
Palifermin
180 mcg/kg 3 days prior to chemotherapy
Placebo
Single dose 3 days prior to chemotherapy
Adriamycin (Doxorubicin)
30 mg/m\^2 IV continuous infusion for 72 hours; days 0, 1, 2 (infusion completing on day 3) (total dose = 90 mg/m\^2).
Ifosfamide
2.5 g/m\^2 IV bolus over 3 hours, days 0,1, 2, 3 (total dose = 10 g/m\^2); for patients receiving the AI Regimen.
Vincristine
2 mg IV on day 0, for patients with small cell histology receiving the AI Regimen.
Cisplatin
120 mg/m\^2 on day 0, for patients receiving the AP Regimen.
U.T.M.D. Anderson Cancer Center, Houston
M.D. Anderson Cancer Center
OTHER