The Efficacy and Safety of Pegylated Liposomal Doxorubicin Compared With Capecitabine as First Line Chemotherapy for Metastatic Breast Cancer (P04445/MK-2746-071)

PHASE3CompletedINTERVENTIONAL
Enrollment

210

Participants

Timeline

Start Date

January 13, 2006

Primary Completion Date

September 29, 2010

Study Completion Date

October 18, 2010

Conditions
Breast Cancer
Interventions
DRUG

Pegylated liposomal doxorubicin (SCH 200746)

pegylated liposomal doxorubicin (50 mg/m\^2 q 28 days) was administered intravenously until disease progression or unacceptable toxicity

DRUG

Capecitabine

capecitabine (1250 mg/m\^2 BID x 14 days q 21 days) in tablets of 150 mg and 500 mg was administered orally, until disease progression or unacceptable toxicity

All Listed Sponsors
collaborator

Essex Pharma GmbH

INDUSTRY

lead

Merck Sharp & Dohme LLC

INDUSTRY

NCT00266799 - The Efficacy and Safety of Pegylated Liposomal Doxorubicin Compared With Capecitabine as First Line Chemotherapy for Metastatic Breast Cancer (P04445/MK-2746-071) | Biotech Hunter | Biotech Hunter