51
Participants
Start Date
October 31, 2004
Primary Completion Date
December 31, 2008
Study Completion Date
December 31, 2008
Niacin
Subjects randomized to Niacin therapy will be treated with Niacin at night for 16 wks to reduce plasma free fatty acid concentrations. The dose of medication will be gradually increased: 500 mg/day during week 1, 1000 mg/day during week 2, 1500 mg/day during week 3, and 2000mg/day during weeks 4-16.
fenofibrate
Subjects randomized to fenofibrate will be treated with 200 mgs per day for eight weeks.
placebo
Subjects randomized to placebo will be treated with one placebo pill per day for eight weeks.
Washington University School of Medicine, St Louis
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Washington University School of Medicine
OTHER