43
Participants
Start Date
October 31, 2005
Primary Completion Date
September 4, 2013
Study Completion Date
September 4, 2013
Doxorubicin
60 mg/m2 IV, bolus once a day every 14 days x 2-4 cycles
Cyclophosphamide
600 mg/m2 IV once a day every 14 days x 2-4 cycles
Carboplatin
AUC 2 IV weekly for 9-12 doses beginning two weeks after completion of last AC dose
Nab-paclitaxel
100 mg/m2 IV over 30 min weekly for 9-12 doses beginning two weeks after completion of last AC dose
GM-CSF
250 μg/mL IV or on day 4-13 of each subcutaneous cycle of doxorubicin and injection cyclophosphamide
Trastuzumab
4mg/kg, and then2 mg/kg q wk IV weekly for 12-16 doses beginning two weeks after completion of last AC dose
Bevacizumab
10mg/kg q 2 wks
Chao Family Comprehensive Cancer Center, Orange
University of California, Irvine
OTHER