224
Participants
Start Date
November 30, 2005
Primary Completion Date
August 31, 2011
Study Completion Date
August 31, 2011
Lithium (LI)
The starting LI dose will be 150 mg in the morning and evening. The dose of medication will be adjusted to achieve plasma LI level ranges between 0.40 and 0.99 mEq/L (target 0.80 to 0.99 mEq/L).
Divalproex (DV)
Dosage of DV will be 250 mg in the morning and evening. The dose of medication will be adjusted to achieve plasma DV level ranges between 40 and 99 mcg/mL (target 80 to 99 mcg/ml).
Weill Cornell Medical College, White Plains
University of Pittsburgh, Pittsburgh
University of Pennsylvania, Philadelphia
Duke University Medical Center, Durham
Precise Research Centers, Flowood
University Hospitals Case Medical Center, Cleveland
Baylor College of Medicine, Houston
Centre for Addiction and Mental Health, Toronto
National Institute of Mental Health (NIMH)
NIH
Weill Medical College of Cornell University
OTHER