Effect of Polymorphisms in the Adenosine a2a Receptor Gene and AMPD2 Gene on Adenosine-Induced Vasodilation and Reactive Hyperemia

NACompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

November 30, 2005

Study Completion Date

February 28, 2006

Conditions
Blood Flow in Healthy Volunteers
Interventions
DRUG

Intra-arterial infusion of adenosine

DRUG

intra-arterial infusion of caffeine

DRUG

intra-arterial infusion of acetylcholine

DRUG

intra-arterial infusion of sodium nitroprusside

PROCEDURE

Occlusion of arm-circulation by inflation of upper-arm cuff to 200mmHg for 2, 5 and 13 minutes

Trial Locations (1)

6500HB

Radboud University Nijmegen Medical Centre, Nijmegen

All Listed Sponsors
collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

lead

Radboud University Medical Center

OTHER

NCT00253929 - Effect of Polymorphisms in the Adenosine a2a Receptor Gene and AMPD2 Gene on Adenosine-Induced Vasodilation and Reactive Hyperemia | Biotech Hunter | Biotech Hunter