A Study of Efalizumab in Participants With Moderate to Severe Chronic Psoriasis Who Have Failed, Have a Contraindication to, or Are Intolerant of Other Systemic Therapies

PHASE4CompletedINTERVENTIONAL
Enrollment

1,266

Participants

Timeline

Start Date

December 13, 2004

Primary Completion Date

January 25, 2007

Study Completion Date

January 25, 2007

Conditions
Psoriasis
Interventions
DRUG

Efalizumab - anti-CD11a recombinant human monoclonal antibody

Participants will receive efalizumab 1.0 milligram per kilogram (mg/kg) (with an initial conditioning dose of 0.7 mg/kg) once weekly by subcutaneous injection for 12 weeks (first treatment \[FT\]). Depending on the response at Week 12, participants could receive additional 8 to 12 weekly injections of efalizumab 1.0 mg/kg.

Trial Locations (1)

Unknown

Medical Information, Feltham

All Listed Sponsors
lead

Merck KGaA, Darmstadt, Germany

INDUSTRY

NCT00249808 - A Study of Efalizumab in Participants With Moderate to Severe Chronic Psoriasis Who Have Failed, Have a Contraindication to, or Are Intolerant of Other Systemic Therapies | Biotech Hunter | Biotech Hunter