Vicriviroc (SCH 417690) in Combination Treatment With Optimized ART Regimen in Experienced Participants (VICTOR-E1) (MK-7690-020/P03672)

PHASE2CompletedINTERVENTIONAL
Enrollment

116

Participants

Timeline

Start Date

September 19, 2005

Primary Completion Date

October 19, 2007

Study Completion Date

March 17, 2011

Conditions
HIV Infections
Interventions
DRUG

Vicriviroc 30 mg

Three tablets of vicriviroc 10 mg once daily for 48 weeks (Double-blind Period) or for up to 45 months (Open Label Period).

DRUG

Vicriviroc 20 mg

Two tablets of vicriviroc 10 mg once daily for 48 weeks.

DRUG

Placebo

Three tablets of placebo once daily for 48 weeks.

DRUG

Placebo

Two tablets of placebo once daily for 48 weeks.

DRUG

Background ART Regimen

"An open-label ritonavir-boosted optimized background ART regimen containing ≥3 drugs (including a protease inhibitor \[PI\]) selected for each individual study participant by the investigator. The optimized regimens most commonly include new nucleoside analogs (NRTIs) and a PI, usually boosted with concomitant ritonavir."

All Listed Sponsors
lead

Merck Sharp & Dohme LLC

INDUSTRY

NCT00243230 - Vicriviroc (SCH 417690) in Combination Treatment With Optimized ART Regimen in Experienced Participants (VICTOR-E1) (MK-7690-020/P03672) | Biotech Hunter | Biotech Hunter