Evaluation of Chemotherapy Prior to Surgery With or Without Zometa for Women With Locally Advanced Breast Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

October 31, 2002

Primary Completion Date

August 31, 2007

Study Completion Date

May 31, 2011

Conditions
Breast Neoplasms
Interventions
DRUG

Zometa

DRUG

Epirubicin

DRUG

Docetaxel

DRUG

Trastuzumab

ONLY for patients that are Her-2 overexpressing by 3+ by ICH for FSH

RADIATION

External beam radiation

PROCEDURE

Modified radical mastectomy or breast conserving surgery with axillary lymph node dissection

Trial Locations (1)

63110

Washington University School of Medicine, St Louis

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

Novartis

INDUSTRY

collaborator

Pfizer

INDUSTRY

lead

Washington University School of Medicine

OTHER