13
Participants
Start Date
March 31, 2003
Primary Completion Date
September 30, 2009
Study Completion Date
November 30, 2014
Docetaxel
20 mg/m2, 75 mg/m2 infusion
Carboplatin
AUC of 2 and 6 infusion
Radiation therapy
NEOADJUVANT RADIOTHERAPY Radiation therapy will be concurrent with the chemotherapy. Radiation therapy will begin within 24 hours of chemotherapy. CONSOLIDATION RADIOTHERAPY Patients with positive surgical margins or incomplete resection (tumor shaved from spine or great vessels) will receive an additional boost of radiotherapy 3 to 6 weeks after surgery. This will be a 16 Gy boost given with concurrent weekly chemotherapy as during the neoadjuvant period.
Surgical resection
All patients will be taken to surgical excision, unless they have developed a condition other than progressive disease, which would make surgery unsafe.
Stanford University School of Medicine, Stanford
Collaborators (1)
Aventis Pharmaceuticals
INDUSTRY
Stanford University
OTHER