Trastuzumab and Letrozole in Treating Postmenopausal Women With Progressive Advanced Breast Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

13

Participants

Timeline

Start Date

May 31, 2005

Primary Completion Date

January 31, 2010

Study Completion Date

April 30, 2011

Conditions
Breast Cancer
Interventions
DRUG

Trastuzumab + Letrozole

Patients receive trastuzumab (Herceptin®) IV over 30-90 minutes once in weeks 1-3 OR once in week 1. Courses repeat every 3 weeks in the absence of disease progression or unacceptable toxicity. Patients experiencing disease progression after 9 weeks receive trastuzumab as before and oral letrozole once daily in the absence of further disease progression or unacceptable toxicity.

Trial Locations (14)

CH-5001

Kantonspital Aarau, Aarau

CH-5404

Kantonsspital Baden, Baden

CH-4016

Saint Claraspital AG, Basel

CH-4031

Universitaetsspital-Basel, Basel

CH-3010

Inselspital Bern, Bern

CH-4101

Kantonsspital Bruderholz, Bruderholz

CH-7000

Kantonsspital Graubuenden, Chur

CH-1011

Centre Hospitalier Universitaire Vaudois, Lausanne

CH-4410

Kantonsspital Liestal, Liestal

CH-6850

Ospedale Beata Vergine, Mendrisio

CH-4310

Praxis Dr. Beretta, Rheinfelden

CH-9007

Kantonsspital - St. Gallen, Sankt Gallen

CH-8063

City Hospital Triemli, Zurich

CH-8091

UniversitaetsSpital Zuerich, Zurich

All Listed Sponsors
lead

Swiss Cancer Institute

OTHER

NCT00238290 - Trastuzumab and Letrozole in Treating Postmenopausal Women With Progressive Advanced Breast Cancer | Biotech Hunter | Biotech Hunter