Lofexidine for Inpatient Opiate Detox

PHASE3CompletedINTERVENTIONAL
Enrollment

264

Participants

Timeline

Start Date

June 30, 2006

Primary Completion Date

October 31, 2007

Study Completion Date

October 31, 2007

Conditions
Opiate Addiction
Interventions
DRUG

Lofexidine

Lofexidine is an alpha2-adrenergic-agonist with mild to moderate antihypertensive actions. It is mainly used in the alleviation of opioid withdrawal signs and symptoms.

DRUG

Placebo

Placebo is an exact match of lofexidine, less the active ingredient.

Trial Locations (16)

10304

Richmond Medical Center, Staten Island

19104

VA Medical Center, Philadelphia, Philadelphia

20016

CNS Psychiatric Institute of Washington, Washington D.C.

21201

VA Maryland Health Care System, Baltimore, Baltimore

30308

Atlanta Center for Medical Research, Atlanta

40502

University of Kentucky, Lexington

48207

Wayne State University School of Medicine, Detroit

53213

Aurora Psychiatric Hospital, Wauwatosa

60194

Alexian Center for Psychiatric Research, Hoffman Estates

75234

Research Across America, Dallas

84148

VA Salt Lake City Health Care System, Salt Lake City, Salt Lake City

90703

CNS, Cerritos, Cerritos

98108

VA Puget Sound Health Care System, Seattle, Seattle

02908

VA Medical Center, Providence, Providence

37232-8650

Psychiatric Hospital at Vanderbilt, Nashville

78229-3900

University of Texas Health Science Center at San Antonio, San Antonio

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

collaborator

USWM, LLC (dba US WorldMeds)

INDUSTRY

lead

US Department of Veterans Affairs

FED

NCT00235729 - Lofexidine for Inpatient Opiate Detox | Biotech Hunter | Biotech Hunter