The Effect of Fructose on Blood Fats in Dialysis Patients and Healthy Volunteers

NACompletedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

September 30, 2004

Primary Completion Date

October 31, 2008

Study Completion Date

October 31, 2009

Conditions
End-stage Renal Disease
Interventions
PROCEDURE

oral fructose and high fat diet

"High fat diet: The composition will be: 35% of energy as fat, 50% carbohydrate, 15% protein (\~1.3 g/kg), sat:mono:poly 1:3:1, cholesterol 200 mg/d, 30% starch,15% sugar, 3% fructose, and 25 gm fiber/d. This relatively high fat diet, which falls within the recommendations by the National Kidney Foundation for hemodialysis patients, will suppress fatty acid synthesis in normal volunteers.~Fructose in 360 ml water will be orally administered as 1.4 g/kg (\~100 g or 400 kcal for a 70 kg person), divided into 30 mL (1 ounce) doses given every 1/2h for 6 hours."

Trial Locations (1)

10021

Rockefeller University Hospital, New York

All Listed Sponsors
collaborator

Robert C. Atkins Foundation

OTHER

collaborator

The Rogosin Institute

OTHER

lead

Rockefeller University

OTHER

NCT00234156 - The Effect of Fructose on Blood Fats in Dialysis Patients and Healthy Volunteers | Biotech Hunter | Biotech Hunter