When to Start Anti-HIV Drugs in Children Infected With HIV (The PREDICT Study)

PHASE3CompletedINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

April 30, 2006

Primary Completion Date

September 30, 2011

Study Completion Date

September 30, 2011

Conditions
HIV Infections
Interventions
DRUG

Abacavir

8 mg/kg (up to 300 mg/dose) take orally twice daily

DRUG

Efavirenz

200 to 600 mg taken orally once daily

DRUG

Lamivudine

4 mg/kg (up to 150 mg/dose) taken orally twice daily

DRUG

Lopinavir/Ritonavir

230 mg/57.5 mg/m\^2 body surface area taken orally twice daily with food

DRUG

Nelfinavir

45-55 mg/kg taken orally twice daily with food

DRUG

Nevirapine

120 mg/m\^2 once daily for first 14 days, tehn 200 mg/m\^2 (up to 400 mg/day) twice daily

DRUG

Zidovudine

180-240 mg/m\^2 every 12 hours (up to 300 mg/dose)

Trial Locations (9)

10330

Hiv-Nat Cipra Crs, Pathumwan

11000

Bamrasnaradura Institute CIPRA CRS, Nonthaburi

20110

Queen Savang Vadhana Memorial Hosp. CIPRA CRS, Chon Buri

22000

Prapokklao Hosp. CIPRA CRS, Chanthaburi

40002

Srinagarind Hosp. CIPRA CRS, Khon Kaen

50180

Nakornping Hosp. CIPRA CRS, Chiang Mai

57000

Chiang Rai Regional Hosp. CIPRA CRS, Muang

Unknown

National Pediatric Hosp., Cambodia CIPRA CRS, Phnom Penh

Social Health Clinic, Cambodia CIPRA CRS, Phnom Penh

All Listed Sponsors
collaborator

Comprehensive International Program of Research on AIDS

OTHER

lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT00234091 - When to Start Anti-HIV Drugs in Children Infected With HIV (The PREDICT Study) | Biotech Hunter | Biotech Hunter