NCT00231569 - Dose-escalating Safety Study in Subjects on Stable Statin Therapy | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 30, 2005

Primary Completion Date

June 30, 2007

Study Completion Date

December 31, 2007

Conditions

Hypercholesterolemia

Interventions

DRUG

ISIS 301012 or Placebo

30 mg subcutaneous injection on days 1, 8, 10, 12, 15, 22, and 29

DRUG

ISIS 301012 or Placebo

100 mg subcutaneous injection on days 1, 8, 10, 12, 15, 22, and 29

DRUG

ISIS 301012 or Placebo

200 mg subcutaneous injection on days 1, 8, 10, 12, 15, 22, and 29

DRUG

ISIS 301012 or Placebo

300 mg subcutaneous injection on days 1, 8, 10, 12, 15, 22, and 29

DRUG

ISIS 301012 or Placebo

400 mg subcutaneous injection on days 1, 8, 10, 12, 15, 22, and 29

DRUG

ISIS 301012 or Placebo

200 mg subcutaneous injection on days 1, 8, 10, 12, 15, 22, 29, 36, 43, 50, 57, 64, 71, 78, and 85

DRUG

ISIS 301012 or Placebo

300 mg subcutaneous injection on days 1, 8, 10, 12, 15, 22, 29, 36, 43, 50, 57, 64, 71, 78, and 85

Trial Locations (5)

Auburn

Amsterdam

Leiden

Rotterdam

Utrecht