400
Participants
Start Date
January 31, 1998
Primary Completion Date
July 31, 2007
Study Completion Date
January 31, 2010
ACE Inhibition
ACE inhibitor ramipril (6 mg/m²/day) will be given to all subjects.
Intensified Blood Pressure Control
Any antihypertensive drugs except ACE inhibitors and angiotensin receptor blockers will be allowed.
Add-on Angiotensin Receptor Blockade
In patients who show persistent or breakthrough proteinuria at the end of the initial study period, telmisartan (50 mg/m²/day) will be added to the existing medication.
Semmelweis University Budapest, 1st Department of Pediatrics, Budapest
Vilnius University Children's Hospital, Pediatric Department, Nephrology Unit, Vilnius
University Children's Hospital, Nephrology Unit, Zurich
Ospedale Infantile Regina Margherita, U.O.A. Nefrologia, Dialisi, Trapianto, Torino
Faculty of Medicine Belgrade, University Children's Hospital, Nephrology Unit, Belgrade
Humboldt University Berlin, Charité Children's Hospital, Department of Pediatric Nephrology, Berlin
Karolinska Institute, Huddinge University Hospital, Dept. of Pediatrics, Stockholm
G.Gaslini Institute, Nephrology Unit, Genoa
University Children's Hospital, Dept. of Nephrology, Rostock
Azienda Ospedaliera, Istitui Clinici di Perfezionamento, Servizio die Emodialisi Pediatrica, Milan
University Hospital Hamburg-Eppendorf, University Children's Hospital, Dept. of Pediatric Nephrology, Hamburg
Hannover Medical School, Children's Hospital Div. II, Pediatric Nephrology, Hanover
Istanbul University, Cerrahpasa Medical Faculty, Dept, of Pediatrics, Istanbul
University of Istanbul, Istanbul Medical Faculty, Dept. of Pediatrics, Istanbul
Philipps University Marburg, Dept. of Pediatrics, Marburg
Ege University Medical Faculty, Dept. of Pediatric Nephrology, Izmir
Azienda Ospedaliera die Padova. U.O. Nefrologia Dialisi e Trapianto - Dipartimento di Pediatria, Padua
University Hospital Essen, Department of Pediatrics, Pediatric Nephrology Unit, Essen
Johannes Gutenberg University Mainz, Department of Pediatrics,, Mainz
Hopiteaux Universitaires de Strasbourg, Strasbourg
Division of Pediatric Nephrology, Children's Hospital, University of Heidelberg, Heidelberg
Hopital Necker, Division of Pediatric Nephrology, Paris
Inserm U574, Paris
University Hospital Motol, 1st Department of Pediatrics, Prague
Urban Hospital St. Georg, Department of Pediatrics, Pediatric Nephrology Unit, Leipzig
Ospedale Pediatrico Bambino Gesù, Division of Nephrology and Dialysis, Rome
Medical University of Gdansk, Pediatric Nephrology Department, Gdansk
Jagellonian University Medical College, Department of Pediatric Nephrology, Krakow
Clinic of Pediatrics, Pomeranian Academy of Medicine, Szczecin
Children's Memorial Health Hospital, Nephrology and Kidney Transplantation Department, Warsaw
Hospital S. Joao-Faculade de Medicina do Porto, Dept. of Pediatrics, Porto
Cukurova University School of Medicine, Dept. of Pediatric Nephrology, Adana
Hacettepe University, Faculty of Medicine, Pediatric Nephrology and Rheumatology, Ankara
Collaborators (2)
European Commission
OTHER
Boehringer Ingelheim
INDUSTRY
Baxter Healthcare Corporation
INDUSTRY
Aventis Pharmaceuticals
INDUSTRY
Heidelberg University
OTHER