39
Participants
Start Date
October 31, 2004
Primary Completion Date
November 30, 2012
Study Completion Date
January 31, 2013
Bevacizumab
Must be administered 1st before Docetaxel \& Oxaliplatin.7.5 mg/kg, IV, day 1 of each cycle; During the first cycle, bevacizumab will be delivered over 90 + or - 15 minutes. If the 1st IV infusion is tolerated w/o infusion-associated adverse events, the 2nd infusion may be delivered over 60 + or - 10 minutes. If the 60 min infusion is well tolerated, all subsequent infusions may be delivered over 30 min + or - 10 mins.
Docetaxel
Must be administered 2nd after Bevacizumab and followed by Oxaliplatin.70 mg/m(2), IV over 60 minutes, day 1 of each cycle;
Oxaliplatin
Must be administered 3rd after Bevacizumab and Docetaxel. 75 mg/m(2), IV over 120 minutes, Day 1 of each cycle.
Veterans Affairs Medical Center - Detroit, Detroit
University of Michigan Comprehensive Cancer Center, Ann Arbor
Barbara Ann Karmanos Cancer Institute, Detroit
Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center, Columbus
National Cancer Institute (NCI)
NIH
Barbara Ann Karmanos Cancer Institute
OTHER