84
Participants
Start Date
August 31, 2004
Primary Completion Date
November 30, 2012
Study Completion Date
October 31, 2015
ifosfamide and doxorubicin vs gemcitabine and docetaxel
"Arm 1 will consist of the two drug combination of doxorubicin and ifosfamide (with mesna) Treatment will be delivered over 3 days at 21 day intervals. Patients will receive filgrastim days 4-10 or peg-filgrastim on day 4 as a myeloid growth factor.~Arm 2 will consist of the two drug combination of gemcitabine (day 1, 8) and docetaxel (day 8) repeated at 21 day intervals. Patients will receive filgrastim as a myeloid growth factor days 9-15 or peg-filgrastim on day 4.~All patients will receive 4 cycles of chemotherapy unless there is unacceptable toxicity or disease progression that may adversely impact the surgical plan for complete resection."
University of Michigan Comprehensive Cancer Center, Ann Arbor
University of Michigan Rogel Cancer Center
OTHER