Breathing Regulation Training for Individuals With Panic Disorder

NACompletedINTERVENTIONAL
Enrollment

136

Participants

Timeline

Start Date

March 31, 2005

Primary Completion Date

November 30, 2008

Study Completion Date

November 30, 2008

Conditions
Panic Disorder
Interventions
BEHAVIORAL

Raise-CO2 breathing regulation training

Reverse hyperventilation (defined by low arterial CO2) is often characteristic of individuals with panic disorder. Participants will be randomly assigned to one of three groups: raise-CO2 breathing, lower-CO2 breathing, or a control group. Participants in the raise-CO2 group will be taught techniques to recover from hyperventilation faster.

BEHAVIORAL

Lower-CO2 breathing regulation training

According to the false suffocation alarm theory, anxiety is experienced when an overly sensitive hypothalamic mechanism is triggered by rising pCO2. Participants in the lower-CO2 group will be taught techniques to reach hyperventilation levels, then switch to breathing techniques that reduce hyperventilation symptoms.

BEHAVIORAL

Control

Participants in the control group will not be taught any breathing techniques but will be included in all assessments.

Trial Locations (1)

94304

Stanford University & VA Health Care System, Palo Alto

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Stanford University

OTHER

NCT00183521 - Breathing Regulation Training for Individuals With Panic Disorder | Biotech Hunter | Biotech Hunter