Combination Chemotherapy, Radiation Therapy and Surgery for Esophageal Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

August 31, 2004

Primary Completion Date

November 30, 2007

Study Completion Date

November 30, 2014

Conditions
Adenocarcinoma of EsophagusSquamous Cell Carcinoma of Esophagus
Interventions
DRUG

Cetuximab

Given once per week on weeks 1-8 and restarted 4 weeks after surgery, once weekly for 6 months.

DRUG

Cisplatin

Given once per week on weeks 1, 2, 4,and 5.

DRUG

Irinotecan

Given once per week on weeks 1, 2, 4,and 5.

DEVICE

Radiation therapy

Once daily for 28 treatments (5 1/2 weeks)

PROCEDURE

Surgery

Surgery performed 4-8 weeks after chemoradiation therapy.

Trial Locations (2)

02115

Dana-Farber Cancer Institute, Boston

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

Brigham and Women's Hospital

OTHER

lead

Dana-Farber Cancer Institute

OTHER

NCT00165490 - Combination Chemotherapy, Radiation Therapy and Surgery for Esophageal Cancer | Biotech Hunter | Biotech Hunter