Taxotere, Cisplatin and Irinotecan (CPT-11) for Esophagogastric Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

54

Participants

Timeline

Start Date

August 31, 2001

Primary Completion Date

March 31, 2005

Study Completion Date

April 30, 2009

Conditions
Esophageal CancerGastric CancerGE Junction Cancer
Interventions
DRUG

Taxotere

Given once weekly for 2 weeks followed by a one week rest period (1 cycle is 3 weeks) Participants may continue on treatment unless there is disease progression or intolerable toxicities.

DRUG

Cisplatin

Given once weekly for 2 weeks followed by a one week rest period (1 cycle is 3 weeks) Participants may continue on treatment unless there is disease progression or intolerable toxicities.

DRUG

Irinotecan

Given once weekly for 2 weeks followed by a one week rest period (1 cycle is 3 weeks) Participants may continue on treatment unless there is disease progression or intolerable toxicities.

Trial Locations (3)

02114

Massachusetts General Hospital, Boston

02115

Beth Israel Deaconess Medical Center, Boston

02130

Faulkner Hospital, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Massachusetts General Hospital

OTHER

collaborator

Beth Israel Deaconess Medical Center

OTHER

collaborator

Brigham and Women's Hospital

OTHER

collaborator

Aventis Pharmaceuticals

INDUSTRY

lead

Dana-Farber Cancer Institute

OTHER