Monitoring Highly Active Antiretroviral Therapy in HIV-infected Parents in Thailand

PHASE3CompletedINTERVENTIONAL
Enrollment

716

Participants

Timeline

Start Date

May 31, 2005

Primary Completion Date

April 30, 2010

Study Completion Date

December 31, 2011

Conditions
HIV Infections
Interventions
PROCEDURE

Antiretroviral Drug Combination Switching Criteria

Antiretroviral treatment will use the standard viral load (VL) based monitoring strategy, where switching is performed when VL is confirmed (within one month) above 400 copies per mL.

PROCEDURE

Antiretroviral Drug Combination Switching Criteria

Antiretroviral treatment is monitored using a CD4 based monitoring strategy where switching is performed when a confirmed (within one month) relative decline in CD4 count of more than 30% from peak values is observed within 200 cells from baseline.

Trial Locations (20)

10220

Buddhachinaraj Hospital, Bangkok

10280

Samutprakarn Hospital, Samutprakarn

20000

Chonburi Hospital, Muang, Chonburi

21000

Rayong Hospital, Rayong

22000

Prapokklao Hospital, Prapokklao, Muang

24000

Chacheongsao Hospital, Chacheongsao

30000

Maharaj Nakornratchasrima Hospital, Muang, Nakornratchasrima

40000

Regional Health Promotion Centre 6,, Khon Kaen

43000

Nong Khai Hospital, Muang, Nong Khai

44000

Mahasarakam Hospital, Muang

50120

Sanpatong Hospital, Sanpatong

50180

Nakornping Hospital, Mae Rim

51000

Lamphun Hospital, Muang

52000

Lampang Hospital, Lampang

56000

Phayao Provincial Hospital, Muang

57000

Chiangrai Prachanukroh Hospital, Muang, Chiangrai

57110

Mae Chan Hospital, Mae Chan

70000

Ratchaburi Hospital, Muang, Ratchaburi

74000

Samutsakorn Hospital, Muang, Samutsakorn

90110

Hat Yai Hospital, Hat Yai

All Listed Sponsors
collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

Harvard School of Public Health (HSPH)

OTHER

lead

Institut de Recherche pour le Developpement

OTHER_GOV

NCT00162682 - Monitoring Highly Active Antiretroviral Therapy in HIV-infected Parents in Thailand | Biotech Hunter | Biotech Hunter