2,419
Participants
Start Date
January 31, 2005
Primary Completion Date
April 30, 2008
Study Completion Date
June 30, 2008
sulphadoxine-pyrimethamine
mefloquine
Chlorproguanil-dapsone
Placebo
Placebo
Sulphadoxine-pryrimethamine
IPTi doses 1 and 2, at ages 2 and 3 months, sulphadoxine 250mg, pyrimethamine 12.5mg IPTi doses 3, at 9 months of age, sulphadoxine 500mg, pyrimethamine 25mg
IPTi mefloquine
IPTi doses 1 \& 2 at ages 2 \& 3 months, mefloquine 125mg IPTi dose 3 at 9 months, mefloquine 250mg
Chlorproguanil dapsone
IPTi doses 1 and 2 at ages 2 and 3 months, doses 15mg chlorproguanil and 18.75mg dapsone IPTi dose 3 at 9 months of age, doses 22.5mg chlorproguanil and 28.13mg dapsone
Ministry of Health, Korogwe and Same District MCH clinics, Tanga
University of Copenhagen
OTHER
National Institute for Medical Research, Tanzania
OTHER_GOV
Kilimanjaro Christian Medical Centre, Tanzania
OTHER
London School of Hygiene and Tropical Medicine
OTHER