76
Participants
Start Date
October 31, 2004
Primary Completion Date
February 28, 2009
Study Completion Date
February 28, 2009
Pimozide
Each capsule of active treatment will contain 2 mg of pimozide. Dosing will be flexible and will range from a minimum of 2 mg per day to 8 mg per day. Dosing will begin at Week 1 with 1 capsule per day. This will be slowly titrated at a rate of 1 capsule per week to a maximum of 4 capsules depending upon clinical response and side effects.
Placebo
Active drug and placebo will be encapsulated in an identical fashion. The placebo capsule will be made to match in appearance and weight. There will be flexible dosing, allowing a minimum of 1 capsule per day to 4 capsules per day, in order to match the dosing range of the active treatment.
Icahn School of Medicine at Mount Sinai, New York
Manhattan Psychiatric Center, New York
Pilgrim Psychiatric Center, W. Brentwood
National Institute of Mental Health (NIMH)
NIH
Icahn School of Medicine at Mount Sinai
OTHER