Docetaxel and Carboplatin Followed by Oral Capecitabine, Docetaxel and Radiation for Esophageal Cancer

PHASE1CompletedINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

February 29, 2000

Primary Completion Date

September 30, 2013

Study Completion Date

September 30, 2013

Conditions
Esophageal Neoplasms
Interventions
DRUG

Capecitabine (Xeloda)

"Neoadjuvant Chemotherapy:~Docetaxel every 3 weeks for 2 cycles Carboplatin every 3 weeks for 2 cycles with prophylactic antibiotics and antiemetics as needed.~Concomitant chemotherapy and radiation:~Docetaxel weekly for 5 doses without premedication Capecitabine orally, one dose prior to each fraction of irradiation (28 cycles)."

Trial Locations (1)

03756

Norris Cotton Cancer Center, Lebanon

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Sanofi

INDUSTRY

collaborator

Hoffmann-La Roche

INDUSTRY

lead

Dartmouth-Hitchcock Medical Center

OTHER