A Study of Paclitaxel/Carboplatin With or Without CDP791 in Patients With Lung Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

165

Participants

Timeline

Start Date

August 15, 2005

Primary Completion Date

June 25, 2009

Study Completion Date

June 25, 2009

Conditions
CarcinomaNon-Squamous Non-Small-Cell Lung Cancer
Interventions
DRUG

Carboplatin

"10mg/mL vial AUC6. Dosed intravenously over 15-30 minutes immediately following paclitaxel, Day 0 of each cycle.~Each cycle to be repeated every three weeks for a maximum of six cycles."

DRUG

Paclitaxel

6mg/mL vial 200 mg/m2 iv over three hours, Day 0. Each cycle to be repeated every 3 weeks for a maximum of 6 cycles.

DRUG

CDP791 10mg/kg

CDP791 20mg/mL vial CDP791 diluted (10mg/kg or 20mg/kg) in 0.9% saline will be given as a 200mL iv infusion over approximately 60 minutes following administration of standard chemotherapy.

DRUG

CDP791 20mg/kg

CDP791 20mg/kg CDP791 diluted (10mg/kg or 20mg/kg) in 0.9% saline will be given as a 200mL iv infusion over approximately 60 minutes following administration of standard chemotherapy.

Trial Locations (21)

Unknown

Budapest

Deszk

Mátraháza

Nyíregyháza

Pécs

Krakow

Lodz

Lublin

Olsztyn

Otwock

Poznan

Radom

Szczecin

Torun

Warsaw

Wroclaw

Zabrze

Kazan'

Moscow

Saint Petersburg

Samara

Sponsors

Lead Sponsor

All Listed Sponsors
lead

UCB Pharma

INDUSTRY