Cyclosporine A C-2h Monitoring Versus Tacrolimus C-0h Monitoring in de Novo Liver Transplant Recipients

PHASE4CompletedINTERVENTIONAL
Enrollment

171

Participants

Timeline

Start Date

December 31, 2002

Primary Completion Date

December 31, 2007

Study Completion Date

December 31, 2007

Conditions
Liver Transplant
Interventions
DRUG

Cyclosporine A

DRUG

Tacrolimus

DRUG

Basiliximab

Each patient was given two 20mg doses of Basiliximab as intravenous bolus injection at Day 0 and Day 4 post-transplant surgery.

DRUG

Methylprednisolone

Methylprednisolone was given as an intravenous bolus of 500mg during transplant surgery

DRUG

Prednisone

Post-operatively prednisone was tapered from an initial dose of 20mg/day to zero at 3 months or continued at 5-10mg if the indication for Orthotopic Liver Transplantation (OLTx) was of auto-immune nature.

Trial Locations (1)

Unknown

Novartis, Basel

Sponsors
All Listed Sponsors
lead

Novartis Pharmaceuticals

INDUSTRY