190
Participants
Start Date
February 28, 2005
Primary Completion Date
April 30, 2009
Study Completion Date
May 31, 2009
Prefrontal rTMS
Participants receive 120% motor threshold (MT) over left and right prefrontal cortex. Treatments will be administered daily for 3 weeks. Participants who show signs of improvement may continue Phase I for up to 3 additional weeks.
Antidepressant Regimen
Particpants who acheive remission with rTMS may start antidepressant medication in phase III.
Sham Stimulation
The sham stimulation will mimic the sensation of rTMS but will not induce an intracerebral current. Treatments will be administered daily for 3 weeks.
Columbia University, New York
Brain Stimulation Laboratory, Medical University of South Carolina, Charleston
Emory University, Atlanta
University of Washington, Seattle
National Institute of Mental Health (NIMH)
NIH
Medical University of South Carolina
OTHER