8
Participants
Start Date
January 31, 2005
Primary Completion Date
May 31, 2010
Study Completion Date
May 31, 2010
Ondansetron followed by placebo
Participants will take 16mg of ondansetron daily for the first three months followed by 3 months of placebo. An atypical antipsychotic drug (olanzapine,quetiapine, or aripiprazole) will also be taken throughout the 6 months treatment period.
Placebo followed by Ondansetron
Participants will take placebo daily for the first three months followed by 3 months of 16mg of ondansetron daily. An atypical antipsychotic drug (olanzapine,quetiapine, or aripiprazole) will also be taken throughout the 6 months treatment period.
Denver VAMC, Denver
National Institute of Mental Health (NIMH)
NIH
University of Colorado, Denver
OTHER