Immunologic Memory (Supp. of ATN 024)

PHASE4CompletedINTERVENTIONAL
Enrollment

95

Participants

Timeline

Start Date

August 31, 2005

Primary Completion Date

November 30, 2007

Study Completion Date

November 30, 2007

Conditions
HIV Infections
Interventions
BIOLOGICAL

Engerix B

Standard adult dose for A1; increased adult dose for A2. Doses at Entry, Weeks 4 and 24. Non-responders (\<10 IU/mL of antibody at week 28/4 weeks after dose #3) will receive Engerix-B increased adult dose at Week 48.

BIOLOGICAL

Twinrix for ATN 024

Standard adult dosage, taken at Entry, Weeks 4 and 24. Non-responders (\<10 IU/mL of antibody at week 28/4 weeks after dose #3) will receive Engerix-B increased adult dose at week 48.

BIOLOGICAL

Recombivax

Dosage at entry and week 24; non-responders ((\<10 IU/mL of antibody at week 28/4 weeks after dose #3) will receive 3rd dose of Recombivax during weeks 48-72.

BIOLOGICAL

Twinrix for ATN 025

Doses at Entry and Week 24. Non-responders (\<10 IU/mL of antibody at week 28/4 weeks after dose #3) will receive a dose of Recombivax during week 48-72.

Trial Locations (4)

20010

Children's Hosp Natinal Med Center, Washington D.C.

70112

Tulane Med Center, New Orleans

90027

Childrens Hosp of Los Angeles, Los Angeles

94118

University of California at San Francisco, San Franciso

All Listed Sponsors
collaborator

National Institute on Drug Abuse (NIDA)

NIH

collaborator

National Institute of Mental Health (NIMH)

NIH

collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

University of North Carolina, Chapel Hill

OTHER

NCT00142753 - Immunologic Memory (Supp. of ATN 024) | Biotech Hunter | Biotech Hunter