One Month Dual Antiretroviral Prophylaxis to Prevent Resistance Mutations in Mothers Exposed to Single Dose Nevirapine

PHASE2CompletedINTERVENTIONAL
Enrollment

244

Participants

Timeline

Start Date

December 31, 2004

Primary Completion Date

May 31, 2006

Study Completion Date

February 28, 2009

Conditions
HIV Infections
Interventions
DRUG

Zidovudine (ZDV)

Zidovudine 300 mg, twice daily, for one month postpartum. Note: after July 03, 2005, all women received 200 mg, twice daily, for the same duration.

DRUG

Didanosine (ddI)

250 mg ddI-EC (400 mg if body weight \>60 kg) once daily, starting at the onset of labor and for one month postpartum

Trial Locations (32)

10220

Bhumibol Adulyadej Hospital, Bangkok

Health Promotion Hospital Regional Center I, Bangkok

10280

Samutprakarn Hospital, Samutprakarn

11000

Pranangklao Hospital, Muang

20000

Chonburi Hospital, Muang

20180

Somdej Pranangchao Sirikit Hospital, Chon Buri

21000

Rayong Hospital, Muang

22000

Prapokklao Hospital, Muang

24000

Chacheongsao Hospital, Muang

30000

Maharaj Nakornratchasrima Hospital, Muang

40000

Khon Kaen Hospital, Muang

Regional Health Promotion Centre 6, Khon Kaen, Muang

40002

Srinagarind Hospital, Muang

40170

Kranuan Crown Prince Hospital, Kranuan

43000

Nong Khai Hospital, Muang

45000

Roi-et Hospital, Muang

46000

Kalasin Hospital, Muang

50100

Health Promotion Center Region 10, Muang

50180

Nakornping Hospital, Mae Rim

51000

Lamphun Hospital, Munag

52000

Lampang Hospital, Muang

56110

Chiang Kham Hospital, Chiang Kham

57000

Chiangrai Prachanukroh Hospital, Muang

57110

Mae Chan Hospital, Mae Chan

57120

Phan Hospital, Phan

57130

Mae Sai Hospital, Mae Sai

65000

Buddhachinaraj Hospital, Muang

70000

Ratchaburi Hospital, Muang

71000

Phaholpolphayuhasena Hospital, Munag

73000

Nakhonpathom Hospital, Muang

74000

Samutsakorn Hospital, Muang

90110

Hat Yai Hospital, Hat Yai

All Listed Sponsors
lead

Institut de Recherche pour le Developpement

OTHER_GOV

NCT00142337 - One Month Dual Antiretroviral Prophylaxis to Prevent Resistance Mutations in Mothers Exposed to Single Dose Nevirapine | Biotech Hunter | Biotech Hunter