Addition of Naltrexone to Methadone Taper

PHASE2CompletedINTERVENTIONAL

Enrollment

174

Participants

Timeline

Start Date

April 30, 2005

Study Completion Date

July 31, 2006

Conditions

Heroin DependenceOpioid-Related DisordersSubstance-Related Disorders

Interventions

DRUG

Naltrexone

low dose naltrexone in addition to daily methadone taper

DRUG

Placebo comparator

1 capsule/day for 6 days

DRUG

naltrexone

0.125 mg capsule/day for 6 days

DRUG

naltrexone

0.250 mg capsule/day for 6 days

Trial Locations (1)

Duke University, Durham

All Listed Sponsors

lead

National Institute on Drug Abuse (NIDA)

NIH

NCT00135759 - Addition of Naltrexone to Methadone Taper | Biotech Hunter | Biotech Hunter