275
Participants
Start Date
October 31, 2005
Primary Completion Date
September 30, 2015
Study Completion Date
September 30, 2015
calcineurin inhibitor-based immunosuppression
May be cyclosporine, mycophenolate mofetil, or tacrolimus
liver transplant
Occurs at study entry
corticosteroids
3-month course of corticosteroids
immunosuppression withdrawal
One year after transplantation, participants eligible for withdrawal are randomly assigned in a 4 to 1 ratio to immunosuppression withdrawal or to maintenance.
University of Pennsylvania, Philadelphia
Cleveland Clinic, Cleveland
University of Michigan, Ann Arbor
Northwestern University, Chicago
Baylor University, Dallas
University of Colorado, Denver
University of California, San Francisco, San Francisco
University of Washington, Seattle
Immune Tolerance Network (ITN)
NETWORK
National Institute of Allergy and Infectious Diseases (NIAID)
NIH