180
Participants
Start Date
July 31, 2005
Primary Completion Date
February 28, 2011
Study Completion Date
February 28, 2011
Managed problem solving
Participants in the managed problem solving group will have four study visits and will receive three phone calls for the first 3 months of the study, and one phone call every month for the following 9 months. At each study visit, participants will identify barriers to adherence. During the phone calls, participants will be asked about any steps they have taken to improve their adherence. A medication event monitoring system (MEMS) will be used to assess participants' treatment adherence. MEMS uses microelectronic monitors on the caps of medication bottles to record the timing and frequency of bottle openings. Participants whose adherence has decreased or remained the same at the end of 12 months will be evaluated for regimen changes. Blood collection at the beginning and end of the study will be used to measure viral load and CD4 count.
Standard care
Participants will receive standard of care for 12 months.
University of Pennsylvania School of Medicine, Philadelphia
National Institute of Mental Health (NIMH)
NIH
University of Pennsylvania
OTHER