Managed Problem Solving to Increase Treatment Adherence in Individuals With HIV

NACompletedINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

July 31, 2005

Primary Completion Date

February 28, 2011

Study Completion Date

February 28, 2011

Conditions
HIV Infections
Interventions
BEHAVIORAL

Managed problem solving

Participants in the managed problem solving group will have four study visits and will receive three phone calls for the first 3 months of the study, and one phone call every month for the following 9 months. At each study visit, participants will identify barriers to adherence. During the phone calls, participants will be asked about any steps they have taken to improve their adherence. A medication event monitoring system (MEMS) will be used to assess participants' treatment adherence. MEMS uses microelectronic monitors on the caps of medication bottles to record the timing and frequency of bottle openings. Participants whose adherence has decreased or remained the same at the end of 12 months will be evaluated for regimen changes. Blood collection at the beginning and end of the study will be used to measure viral load and CD4 count.

BEHAVIORAL

Standard care

Participants will receive standard of care for 12 months.

Trial Locations (1)

19104

University of Pennsylvania School of Medicine, Philadelphia

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of Pennsylvania

OTHER

NCT00130273 - Managed Problem Solving to Increase Treatment Adherence in Individuals With HIV | Biotech Hunter | Biotech Hunter