NCT00129246View on ClinicalTrials.gov

Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

December 31, 2004

Study Completion Date

December 31, 2005

Conditions
SmokingNicotine Dependence
Interventions
DRUG

Naltrexone

Participants received naltrexone hydrochloride on the sixth day of bupropion treatment, and the initial dose was 12.5 mg, followed by 25 mg daily for the duration of the 7-week treatment.

DRUG

Bupropion

Starting with the baseline visit, all participants received 150 mg of bupropion SR once per day for 3 days, then twice per day for the duration of the 7-week treatment period.

Trial Locations (1)

06511

Yale University School of Medicine Substance Abuse Treatment Unit, New Haven

All Listed Sponsors
collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

Yale University

OTHER

NCT00129246 - Low-Dose Naltrexone Combined With Bupropion to Stop Smoking With Less Weight Gain | Biotech Hunter | Biotech Hunter