601
Participants
Start Date
November 30, 2004
Primary Completion Date
June 30, 2006
Study Completion Date
December 31, 2008
Amodiaquine+Artesunate
Amodiaquine 10 mg/kg on day 1, then 5 mg/kg on day 2 and 3; Artesunate 4 mg/kg/d for three days
Amodiaquine+Sulfadoxine/Pyrimethamine
Amodiaquine 10 mg/kg on day 1, then 5 mg/kg on day 2 and 3; S/P at 25 mg/kg sulfadoxine and 1.25 mg/kg pyrimethamine single dose
Artemether+Lumefantrine
Artemether 20 mg + Lumefantrine 120 mg 6 dose regimen at 0 and 8 hours on day 1 and twice daily on days 2 and 3:5 kg to \< 15 kg: 1 tab/dose; 15 to 24 kg: 2 tabs/dose; \>35 kg:4 tabs per dose
Assessment Center - Mulago Hospital, Kampala
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
University of California, San Francisco
OTHER