1,052
Participants
Start Date
July 31, 2005
Primary Completion Date
February 29, 2008
Study Completion Date
February 28, 2009
Abatacept
abatacept 10 mg/kg IV monthly, methotrexate weekly, for 24 months
placebo
placebo IV, monthly, methotrexate weekly for 12 months followed by abatacept 10 mg/kg IV monthly, methotrexate weekly for 12 months
methotrexate
Oral, titrated to at least 15 mg per week not to exceed 20 mg per week administered every 28 days from Month 12 to Month 24
Local Institution, Brussels
Local Institution, Brussels
Local Institution, Antwerp
Local Institution, Leuven
Local Institution, Malvern
Local Institution, Hasselt
Local Institution, Berea
Local Institution, Shenton Park
Local Institution, Panorama
Local Institution, Bloemfontein
Regional Rheumatology Associates, Binghamton
Local Institution, Berlin
Local Institution, A Coruña
Altoona Center For Clinical Research, Duncansville
Local Institution, Milan
Local Institution, Rio de Janeiro - Rj
Local Institution, Dijon
Osteoporosis And Clinical Trials Center, Cumberland
Malamet & Klein, Md, Pa, Hagerstown
Local Institution, Hamburg
Arthritis Clinic Of Northern Virginia, P.C., Arlington
Physicians East, Pa, Greenville
Carolina Bone & Joint, Charlotte
Carolina Pharmaceutical Research, Statesville
Low Country Research Center, Charleston
Local Institution, Chihuahua City
Local Institution, Montpellier
Rheumatology Associates Of North Alabama, Huntsville
Local Institution, León
Local Institution, Santander
Local Institution, Seville
Local Institution, Guadalajara
Local Institution, Guadalajara
Local Institution, Guadalajara
Diagnostic Rheumatology And Research, Indianapolis
Local Institution, Metepec
Local Institution, Morelia
Local Institution, Jesi(Ancona)
Local Institution, Poznan
Local Institution, Cuernavaca
Local Institution, Monterrey
Local Institution, Strasbourg
Arthritis Center Of Nebraska, Lincoln
Lion Research, Norman
Health Research Of Oklahoma, Oklahoma City
Lynn Health Sciences Institute, Oklahoma City
Local Institution, Goiânia
Local Institution, San Luis Potosí City
Walter F Chase Md Pa, Austin
Local Institution, Curitiba
Arthritis Assoc And Osteo Ctr Of Col Sprgs, Colorado Springs
Local Institution, Porto Alegre
Talbert Medical Group, Huntington Beach
Local Institution, Moscow
Local Institution, Moscow
New England Research Associates, Llc, Trumbull
Local Institution, São Paulo
Local Institution, São Paulo
Local Institution, St. John's
Local Institution, Kitchener
Local Institution, Toronto
Local Institution, Montreal
Local Institution, Québec
Local Institution, Sherbrooke
Local Institution, Saskatoon
Local Institution, Prague
Local Institution, Nice
Local Institution, Leipzig
Local Institution, Leipzig
Local Institution, D.f.
Local Institution, Amsterdam
Local Institution, Leiden
Local Institution, Nijmegen
Local Institution, Poznan
Local Institution, Warsaw
Local Institution, Ponce
Local Institution, Muckleneuk
Local Institution, Pretoria
Local Institution, Anyang
Local Institution, Daegu
Local Institution, Daejeon
Local Institution, Seoul
Local Institution, Seoul
Local Institution, Seoul
Local Institution, Seoul
Local Institution, Manchester
Local Institution, Glasgow
Local Institution, Leeds
Local Institution, Newcastle
Lead Sponsor
Bristol-Myers Squibb
INDUSTRY