Abatacept in the Treatment and Prevention of Active Systemic Lupus Erythematosus (SLE) Flares in Combination With Prednisone

PHASE2CompletedINTERVENTIONAL
Enrollment

183

Participants

Timeline

Start Date

September 30, 2005

Primary Completion Date

November 30, 2008

Study Completion Date

November 30, 2008

Conditions
Systemic Lupus Erythematosus
Interventions
DRUG

Abatacept

Injectable, intravenous, 10 mg/kg, abatacept every 28 days, 12 months

DRUG

Placebo

Injectable, intravenous, 0 mg, every 28 days, 12 months

DRUG

Prednisone

Tablets, oral, 30 mg, daily for 28 days then taper off, 12 months

DRUG

Abatacept

Injectable, intravenous, 10 mg/kg, every 28 days

Trial Locations (52)

105

Local Institution, Taipei

407

Local Institution, Taichung

833

Local Institution, Kaohsiung City

1200

Local Institution, Brussels

3000

Local Institution, Leuven

3084

Local Institution, Heidelberg

3144

Local Institution, Malvern

3168

Local Institution, Clayton

4001

Local Institution, Berea

4558

Local Institution, Maroochydore

4870

Local Institution, Cairns

7506

Local Institution, Panorama

8036

Local Institution, Graz

10032

Columbia University Medical Center, New York

11203

Suny Downstate Medical Center, Brooklyn

11217

Local Institution, Taipei

13083

Local Institution, Campinas

13125

Local Institution, Berlin

20000

Local Institution, Aguascalientes

20551

Local Institution, Rio de Janeiro - Rj

33076

Local Institution, Bordeaux

33334

Cria Research, Fort Lauderdale

34295

Local Institution, Montpellier

40202

Kentuckiana Center For Better Bone And Joint Health, Louisville

40225

Local Institution, Düsseldorf

44100

Local Institution, Ferrara

58070

Local Institution, Morelia

60637

The University Of Chicago, Chicago

73104

Ok Medical Research Foundations, Oklahoma City

74050

Local Institution, Goiânia

75679

Local Institution, Paris

77479

Texas Research Center, Sugarland

79106

Local Institution, Freiburg im Breisgau

80060

Local Institution, Curitiba

80230

Denver Arthritis Clinic, Denver

85724

University Of Arizona Arthritis Center, Tucson

89128

Kelly, Timothy, Las Vegas

90048

8737 Beverly Blvd., Los Angeles

90808

Office Of Geoffrey S. Dolan, Md, Long Beach

01246

Local Institution, São Paulo

04023900

Local Institution, São Paulo

04027

Local Institution, São Paulo

04233

Local Institution, São Paulo

V5Z 1L7

Local Institution, Vancouver

R3A 1M4

Local Institution, Winnipeg

06726

Local Institution, Mexico City

00716

Local Institution, Ponce

133-792

Local Institution, Seoul

110-744

Local Institution, Seoul

137-040

Local Institution, Seoul

138-736

Local Institution, Seoul

SE1 7EX

Local Institution, London

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY