Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults

PHASE3CompletedINTERVENTIONAL
Enrollment

1,864

Participants

Timeline

Start Date

September 30, 2005

Primary Completion Date

November 30, 2009

Study Completion Date

November 30, 2009

Conditions
HIV Infections
Interventions
DRUG

Abacavir/Lamivudine

600 mg abacavir/300 mg lamivudine tablet taken orally daily

DRUG

Atazanavir

300 mg tablet taken orally daily

DRUG

Efavirenz

600 mg tablet taken orally daily

DRUG

Emtricitabine/Tenofovir disoproxil fumarate

200 mg emtricitabine/300 mg tenofovir disoproxil fumarate tablet taken orally daily

DRUG

Ritonavir

100 mg tablet taken orally daily

DRUG

Abacavir/Lamivudine placebo

Placebo tablet taken orally daily

DRUG

Emtricitabine/Tenofovir disoproxil fumarate placebo

Placebo tablet taken orally daily

Trial Locations (52)

10011

Cornell CRS (7804), New York

Weill Med. College of Cornell Univ., The Cornell CTU -Chelsea (7803), New York

10016

NY Univ. HIV/AIDS CRS (401), New York

10032

HIV Prevention & Treatment CRS (30329), New York

10037

Harlem ACTG CRS (31483), New York

14215

SUNY - Buffalo (Rochester) (1102), Buffalo

14604

AIDS Community Health Ctr. ACTG CRS (1108), Rochester

14642

University of Rochester ACTG CRS (1101), Rochester

15213

Pitt CRS (1001), Pittsburgh

19104

Hosp. of the Univ. of Pennsylvania CRS (6201), Philadelphia

19401

Presbyterian Medical Center - Univ. of PA (6206), Norristown

20007

Georgetown University CRS (GU CRS) (1008), Washington D.C.

21201

IHV Baltimore Treatment CRS (4651), Baltimore

21287

Johns Hopkins Adult AIDS CRS (201), Baltimore

27401

Moses H. Cone Memorial Hospital CRS (3203), Greensboro

27514

Unc Aids Crs (3201), Chapel Hill

Wake County Department of Health (30076), Chapel Hill

27710

Duke University Medical Center Adult CRS (1601), Durham

30308

Emory University, Atlanta

The Ponce de Leon Center CRS (5802), Atlanta

33139

University of Miami AIDS CRS (901), Miami

37232

Vanderbilt Therapeutics CRS (3652), Nashville

43210

The Ohio State Univ. AIDS CRS (2301), Columbus

44106

Case CRS (2501), Cleveland

44109

Metro Health CRS (2503), Cleveland

45267

University of Cincinnati CRS (2401), Cincinnati

46202

Wishard Hospital (2603), Indianapolis

52242

Univ of Iowa Hosp and Clinic (1504), Iowa City

60611

Northwestern University CRS (2701), Chicago

60612

Cook County Hospital Core Center (2705), Chicago

Rush Univ. Med. Ctr. ACTG CRS (2702), Chicago

63110

Washington U CRS (2101), St Louis

75215

Peabody Health Center CRS (31443), Dallas

80045

University of Colorado Hospital CRS (6101), Aurora

90033

Usc Crs (1201), Los Angeles

90035

UCLA CARE Center CRS (601), Los Angeles

90502

Harbor-UCLA Med. Ctr. CRS (603), Torrance

92103

Ucsd, Avrc Crs (701), San Diego

94110

Ucsf Aids Crs (801), San Francisco

94304

Stanford CRS (501), Palo Alto

98104

University of Washington AIDS CRS (1401), Seattle

University of Washington General Clinical Research (1403), Seattle

94305-5107

San Mateo County AIDS Program (505), Stanford

Willow Clinic (507), Stanford

46202-5250

Indiana University Hospital (2601), Indianapolis

02114

Massachusetts General Hospital ACTG CRS (101), Boston

02115

Brigham and Women's Hosp. ACTG CRS (107), Boston

02118

Bmc Actg Crs (104), Boston

02215

Beth Israel Deaconess Med. Ctr., ACTG CRS (103), Boston

02906

The Miriam Hosp. ACTG CRS (2951), Providence

77555-0435

University of Texas, Galveston (6301), Galveston

00935

Puerto Rico-AIDS CRS (5401), San Juan

All Listed Sponsors
collaborator

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

lead

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections

NETWORK

NCT00118898 - Efavirenz or Atazanavir/Ritonavir Given With Emtricitabine/Tenofovir Disoproxil Fumarate or Abacavir/Lamivudine in HIV Infected Treatment-Naive Adults | Biotech Hunter | Biotech Hunter