Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation

NACompletedINTERVENTIONAL
Enrollment

153

Participants

Timeline

Start Date

August 1, 2004

Primary Completion Date

January 31, 2012

Study Completion Date

January 31, 2012

Conditions
Amyotrophic Lateral Sclerosis
Interventions
DEVICE

Early NIPPV

Early intervention with non-invasive positive pressure ventilation (NIPPV) at 80% forced vital capacity (FVC).

DEVICE

Standard NIPPV

Standard of care non-invasive positive pressure ventilation (NIPPV) at 50% forced vital capacity (FVC).

Trial Locations (12)

10003

Beth Israel, New York

10032

Columbia University, New York

13210

SUNY, Syracuse

17033

Pennsylvania State University, Hershey

19103

Drexel University, Philadelphia

33136

University of Miami, Miami

40536

University of Kentucky, Lexington

48202

Henry Ford Hospital, Detroit

54505

University of Vermont, Burlington

78229

University of Texas-San Antonio, San Antonio

80262

University of Colorado, Denver

84132

University of Utah, Salt Lake City

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

Edward Kasaraskis

OTHER

NCT00116558 - Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation | Biotech Hunter | Biotech Hunter