Treatment Protocol for the Use of Sorafenib in Patients With Advanced Renal Cell Carcinoma

PHASE3CompletedINTERVENTIONAL
Enrollment

2,567

Participants

Timeline

Start Date

June 30, 2005

Primary Completion Date

June 30, 2007

Study Completion Date

October 31, 2008

Conditions
Carcinoma, Renal Cell
Interventions
DRUG

Sorafenib (Nexavar, BAY43-9006)

Multi kinase inhibitor: 400 mg of Sorafenib, orally, twice a day, on a continuous basis as a single agent for the treatment of advanced RCC

Trial Locations (320)

1104

Springfield

1107

Springfield

2130

Jamaica Plain

4401

Bangor

5201

Bennington

6520

New Haven

7018

East Orange

7601

Hackensack

10016

New York

10021

New York

10032

New York

10466

The Bronx

10469

The Bronx

10504

Armonk

10549

Mount Kisco

11365

Fresh Meadows

11432

Jamaica

11501

Mineola

11706

Bay Shore

11733

Setauket

11794

Stony Brook

12110

Latham

12601

Poughkeepsie

12801

Glens Falls

13057

East Syracuse

13326

Cooperstown

13502

Utica

13790

Johnson City

14048

Dunkirk

14221

Williamsville

14263

Buffalo

14642

Rochester

15063

Monongahela

16148

Hermitage

16201

Kittanning

16803

State College

17043

Lemoyne

17111

Harrisburg

17403

York

17604

Lancaster

17901

Pottsville

18015

Bethlehem

18105

Allentown

18301

East Stroudsburg

18512

Dunmore

19096

Wynnewood

19104

Philadelphia

19106

Philadelphia

19111

Philadelphia

19114

Philadelphia

20735

Clinton

20815

Chevy Chase

20817

Bethesda

20850

Rockville

21204

Baltimore

21237

Baltimore

21239

Baltimore

21401

Annapolis

22031

Fairfax

22908

Charlottesville

23229

Richmond

23230

Richmond

23235

Richmond

23294

Richmond

23298

Richmond

23502

Norfolk

24501

Lynchburg

25304

Charleston

25702

Huntington

26505

Morgantown

27215

Burlington

27599

Chapel Hill

27834

Greenville

28203

Charlotte

28204

Charlotte

28501

Kinston

28573

Pollocksville

28602

Hickory

29210

Columbia

29403

Charleston

29406

Charleston

North Charleston

29501

Florence

30309

Atlanta

30342

Atlanta

30901

Augusta

31201

Macon

31701

Albany

31904

Columbus

32114

Daytona Beach

32174

Ormond Beach

32207

Jacksonville

32405

Panama City

32501

Pensacola

32514

Pensacola

32610

Gainesville

32806

Orlando

32901

Melbourne

33016

Hialeah

33136

Miami

33140

Miami Beach

33308

Fort Lauderdale

33331

Weston

33486

Boca Raton

33607

Tampa

33705

St. Petersburg

33805

Lakeland

33901

Fort Myers

34474

Ocala

34761

Ocoee

34994

Stuart

35023

Bessemer

35058

Cullman

36608

Mobile

37043

Clarksville

37203

Nashville

38104

Memphis

38119

Memphis

38120

Memphis

40202

Louisville

40207

Louisville

40215

Louisville

40292

Louisville

43213

Columbus

43214

Columbus

43235

Columbus

44124

Mayfield Heights

44195

Cleveland

44203

Barberton

44710

Canton

44718

Canton

45042

Middletown

45236

Cincinnati

45429

Dayton

46038

Fishers

46107

Beech Grove

46254

Indianapolis

46256

Indianapolis

46350

La Porte

46383

Valparaiso

46526

Goshen

46601

South Bend

46902

Kokomo

47715

Evansville

48038

Clinton Township

48043

Mount Clemens

48106

Ann Arbor

48201

Detroit

48202

Detroit

49443

Muskegon

49546

Grand Rapids

49855

Marquette

50010

Ames

50309

Des Moines

51101

Sioux City

51503

Council Bluffs

52001

Dubuqe

52402

Cedar Rapids

52403

Cedar Rapids

53212

Glendale

53215

Milwaukee

53226

Milwaukee

53715

Madison

54301

Green Bay

54401

Wausau

54449

Marshfield

55416

Saint Louis Park

55426

Saint Louis Park

55455

Minneapolis

55805

Duluth

56201

Willmar

57104

Sioux Falls

58108

Fargo

58122

Fargo

58501

Bismarck

59807

Missoula

60426

Harvey

60432

Joliet

60435

Joliet

60637

Chicago

60640

Chicago

60714

Niles

61615

Peoria

61801

Urbana

62526

Decatur

62701

Springfield

63110

St Louis

63136

St Louis

63141

St Louis

64118

Kansas City

64507

Saint Joseph

65804

Springfield

66044

Lawrence

66061

Olathe

66210

Overland Park

67214

Wichita

67502

Hutchinson

68114

Omaha

68122

Omaha

68124

Omaha

68506

Lincoln

68510

Lincoln

69103

North Platte

70006

Metairie

70360

Houma

70506

Lafayette

70809

Baton Rouge

71105

Shreveport

71603

Pine Bluff

71913

Hot Springs

72034

Conway

72205

Little Rock

72764

Springdale

73110

Midwest City

73120

Oklahoma City

73505

Lawton

74136

Tulsa

75230

Dallas

75237

Dallas

75246

Dallas

75701

Tyler

75702

Tyler

76012

Arlington

76104

Fort Worth

76502

Temple

77024

Houston

78212

San Antonio

78229

San Antonio

78245

San Antonio

78705

Austin

78731

Austin

78759

Austin

79106

Amarillo

79701

Midland

80026

Lafayette

80045

Aurora

80210

Denver

80218

Denver

80538

Loveland

80907

Colorado Springs

81601

Glenwood Springs

83814

Coeur d'Alene

84112

Salt Lake City

84403

Ogden

85258

Scottsdale

85304

Glendale

85704

Tucson

87106

Albuquerque

87108

Albuquerque

87505

Santa Fe

89106

Las Vegas

89109

Las Vegas

90025

Los Angeles

90033

Los Angeles

90057

Los Angeles

90095

Los Angeles

90211

Beverly

90813

Long Beach

91010

Duarte

91206

Glendale

92037

La Jolla

92093

La Jolla

92120

San Diego

92270

Rancho Mirage

92346

Highland

92357

Loma Linda

92663

Newport Beach

92708

Fountain Valley

92868

Orange

93309

Bakersfield

93901

Salinas

94086

Sunnyvale

94115

San Francisco

94305

Stanford

94520

Concord

94589

Vallejo

95823

Sacramento

96859

Tamc

97213

Portland

97239

Portland

97504

Medford

97701

Bend

98101

Seattle

98104

Seattle

98405

Tacoma

98503

Lacey

98684

Vancouver

98902

Yakima

99508

Anchorage

06830

Greenwich

06105

Hartford

06457

Middletown

06050

New Britain

06360

Norwich

06489

Southington

06902

Stamford

06611

Trumbull

04074

Scarborough

02215

Boston

01757

Milford

02169

Quincy

03766

Lebanon

03801

Portsmouth

07109

Belleville

07740

Long Branch

07042

Montclair

07962

Morristown

08902

New Brunswick

07112

Newark

08865

Phillipsburg

07901

Summit

02920

Cranston

T6G 1Z2

Edmonton

R3E 0V9

Winnipeg

B3H 2Y9

Halifax

L8V 5C2

Hamilton

N6A 4L6

London

M4N 3M5

Toronto

M5G 2M9

Toronto

H2W 1S6

Montreal

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Bayer

INDUSTRY