Evaluation of Clinical and Microbial Efficacy and Safety of AzaSite Compared to Tobramycin for Bacterial Conjunctivitis (C-01-401-004)

PHASE3CompletedINTERVENTIONAL
Enrollment

743

Participants

Timeline

Start Date

July 31, 2004

Primary Completion Date

October 31, 2005

Study Completion Date

October 31, 2005

Conditions
Bacterial Conjunctivitis
Interventions
DRUG

AzaSite

AzaSite ophthalmic solution; one topical drop to the infected eye or eyes twice daily (in the morning and at bedtime) on Days 1 and 2 followed by once daily (in the morning between 7 and 10am) on Days 3 through 5.

DRUG

Tobramycin

Tobramycin ophthalmic solution; one topical drop to the infected eye or eyes four times daily at 4 to 6 hour intervals (first dose in the morning between 7 and 10am) for 5 days.

Trial Locations (26)

11746

Huntington Medical Group, Huntington Station

15228

Irving Weinberger, MD, Pittsburgh

27262

Cornerstone Eye Care, High Point

29605

Southern Eye Associates, PA, Greenville

32405

Advanced Eye Care, Panama City

33169

Tukoi Institute for Clinical Research, North Miami Beach

33401

Presidential Eye Center, West Palm Beach

33458

Alan Shuster, MD, Jupiter

33462

Palm Beach Eye Associates, Atlantis

34209

The Eye Associates, Bradenton

34652

Pasco Eye Institute, New Port Richey

35205

Renaissance Center, Birmingham

47714

Medisphere Medical Research Center, LLC, Evansville

63141

Ophthalmology Associates, Creve Coeur

64132

Research Eye Care Center, Kansas City

65212

Mason Eye Institute, Columbia

67502

Hutchinson Clinic, Hutchinson

79904

Corona Research Consultants, Inc., El Paso

80122

Children's Eye Physicians, Littleton

83706

Jon Fishburn, MD, Boise

84107

Cottonwood Ophthalmology Associates, Murray

97209

Eye Health Northwest, Portland

98801

Wenatchee Valley Medical Center, Wenatchee

99205

Rockwood Clinic, PS-Eye Center, Spokane

02114

Massachusetts Eye and Ear Infirmary, Boston

08540

Ophthalmology Associates, Princeton

All Listed Sponsors
lead

Merck Sharp & Dohme LLC

INDUSTRY

NCT00105469 - Evaluation of Clinical and Microbial Efficacy and Safety of AzaSite Compared to Tobramycin for Bacterial Conjunctivitis (C-01-401-004) | Biotech Hunter | Biotech Hunter