Study of DOXIL/CAELYX (Pegylated Liposomal Doxorubicin) and VELCADE (Bortezomib) or VELCADE Monotherapy for the Treatment of Relapsed Multiple Myeloma

PHASE3CompletedINTERVENTIONAL
Enrollment

646

Participants

Timeline

Start Date

December 31, 2004

Primary Completion Date

May 31, 2014

Study Completion Date

June 30, 2014

Conditions
Multiple Myeloma
Interventions
DRUG

Bortezomib (VELCADE)

1.3 mg/m\^2 by rapid (bolus) i.v. administration given on Days 1, 4, 8, and 11 of each 21-day cycle for up to 8 cycles.

DRUG

Bortezomib (VELCADE)

1.3 mg/m\^2 by rapid (bolus) i.v. administration given on Days 1, 4, 8, and 11 of each 21-day cycle for up to 8 cycles..

DRUG

Doxorubicin hydrochloride (DOXIL/CAELYX)

mg/m\^2 by i.v. infusion will be given on Day 4 of every 21-day cycle after the administration of bortezomib (VELCADE) for up to 8 cycles.

Trial Locations (108)

Unknown

Alabaster

Surprise

Berkeley

Loma Linda

Los Angeles

Sacramento

Norwalk

Stamford

Jacksonville

Miami

Stuart

West Palm Beach

Altanta

Boise

Indianapolis

Lexington

Metairie

New Orleans

Minneapolis

Hackensack

Chapel Hill

Charlotte

Durham

Portland

Philadelphia

Pittsburgh

North Charleston

Nashville

Buenos Aires

Ciudad de Buenos Aires

La Plata

Mendoza

Adelaide

Darlinghurst

Melbourne

Perth

Sydney

Graz

Innsbruck

Salzburg

Vienna

Wels

Brussels

Ghent

Leuven

Mont-Godinne

Vancouver

Hamilton

Ottawa

Montreal

Québec

N/a N/a

Brno

Olomouc

Praha 2 N/A

Angers Cedex 1 N/A

Bobigny

Créteil

Lille Cedex N/A

Nantes

Pierre-Bénite

Toulouse

Tours

Vandœuvre-lès-Nancy

Haifa

Jerusalem

Petah Tikva

Ramat Gan

Rehovot

Tel Aviv

Amersfoort

Amsterdam

Amsterdam-Zuidoost

Delft

Groningen

Nieuwegein

Nijmegen

Rotterdam

The Hague

Utrecht

Bialystok

Gdansk

Lodz

Lublin

Warsaw

Wroclaw

Coimbra

Lisbon

Porto

Arkhangelsk

Izhevsk

Moscow

Nizhny Novgorod

Novosibirsk

Obninsk

Saint Petersburg

Yekaterinburg

Singapore

Bloemfontein

Cape Town

Johannesburg

Parktown

Pretoria Gauteng

Barcelona

Madrid

Salamanca

Bath

London

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY

NCT00103506 - Study of DOXIL/CAELYX (Pegylated Liposomal Doxorubicin) and VELCADE (Bortezomib) or VELCADE Monotherapy for the Treatment of Relapsed Multiple Myeloma | Biotech Hunter | Biotech Hunter