Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

PHASE2CompletedINTERVENTIONAL
Enrollment

170

Participants

Timeline

Start Date

November 30, 2004

Primary Completion Date

October 31, 2006

Study Completion Date

November 30, 2013

Conditions
Brain and Central Nervous System Tumors
Interventions
DRUG

irinotecan hydrochloride

DRUG

temozolomide

PROCEDURE

adjuvant therapy

RADIATION

radiation therapy

Trial Locations (118)

14263

Roswell Park Cancer Institute, Buffalo

14621

Lipson Cancer and Blood Center at Rochester General Hospital, Rochester

14642

James P. Wilmot Cancer Center at University of Rochester Medical Center, Rochester

15132

UPMC McKeesport, McKeesport

15212

Allegheny Cancer Center at Allegheny General Hospital, Pittsburgh

15213

Hillman Cancer Center at University of Pittsburgh Cancer Institute, Pittsburgh

UPMC Cancer Center at Magee-Womens Hospital, Pittsburgh

UPMC Cancer Center at UPMC Presbyterian, Pittsburgh

15215

UPMC St. Margaret, Pittsburgh

15219

Mercy Hospital of Pittsburgh, Pittsburgh

15232

UPMC - Shadyside, Pittsburgh

15237

UPMC - Passavant Hospital, Pittsburgh

15243

Cancer Center at St. Clair Memorial Hospital, Pittsburgh

15601

UPMC Cancer Center - Arnold Palmer Pavilion, Greensburg

17405

York Cancer Center at Wellspan Health, York

18015

St. Luke's Hospital Cancer Center, Bethlehem

18105

John and Dorothy Morgan Cancer Center at Lehigh Valley Hospital, Allentown

19001

Abington Memorial Hospital, Abington

19010

Bryn Mawr Hospital, Bryn Mawr

19096

CCOP - MainLine Health, Wynnewood

Lankenau Cancer Center at Lankenau Hospital, Wynnewood

19107

Kimmel Cancer Center at Thomas Jefferson University - Philadelphia, Philadelphia

19141

Albert Einstein Cancer Center, Philadelphia

19301

Paoli Memorial Hospital, Paoli

19612

Reading Hospital and Medical Center, West Reading

19718

CCOP - Christiana Care Health Services, Newark

23298

Massey Cancer Center at Virginia Commonwealth University, Richmond

27203

Randolph Hospital, Asheboro

27288

John Smith, Jr./Dalton McMichael Cancer Center at Morehead Memorial Hospital, Eden

27320

Annie Penn Cancer Center, Reidsville

27401

Moses Cone Regional Cancer Center at Wesley Long Community Hospital, Greensboro

27534

Wayne Radiation Oncology, Goldsboro

28801

Mission Hospitals - Memorial Campus, Asheville

29304

CCOP - Upstate Carolina, Spartanburg

29425

Hollings Cancer Center at Medical University of South Carolina, Charleston

30165

Regional Radiation Oncology Center at Rome, Rome

31904

John B. Amos Community Cancer Center, Columbus

32207

Baptist Cancer Institute - Jacksonville, Jacksonville

32610

University of Florida Shands Cancer Center, Gainesville

39581

Regional Cancer Center at Singing River Hospital, Pascagoula

43215

CCOP - Columbus, Columbus

44304

Akron City Hospital, Akron

44307

McDowell Cancer Center at Akron General Medical Center, Akron

44460

Cancer Research UK Medical Oncology Unit at Churchill Hospital & Weatherall Institute of Molecular Medicine - Oxford, Salem

44601

Radiation Oncology Center, Alliance

44691

Cancer Treatment Center, Wooster

44710

Aultman Hospital Cancer Center at Aultman Health Foundation, Canton

45044

Middletown Regional Hospital, Middletown

45267

Charles M. Barrett Cancer Center at University Hospital, Cincinnati

45373

UVMC Cancer Care Center at Upper Valley Medical Center, Troy

45385

Ruth G. McMillan Cancer Center at Greene Memorial Hospital, Xenia

45405

Grandview Hospital, Dayton

45409

David L. Rike Cancer Center at Miami Valley Hospital, Dayton

45428

Veterans Affairs Medical Center - Dayton, Dayton

45429

Charles F. Kettering Memorial Hospital, Kettering

46107

St. Francis Hospital and Health Centers, Beech Grove

48109

University of Michigan Comprehensive Cancer Center, Ann Arbor

48202

Josephine Ford Cancer Center at Henry Ford Hospital, Detroit

49007

West Michigan Cancer Center, Kalamazoo

53051

Community Memorial Hospital, Menomonee Falls

53226

Medical College of Wisconsin Cancer Center, Milwaukee

53792

University of Wisconsin Comprehensive Cancer Center, Madison

54301

St. Vincent Hospital, Green Bay

54601

Gundersen Lutheran Cancer Center at Gundersen Lutheran Medical Center, La Crosse

57701

Rapid City Regional Hospital, Rapid City

60005

Northwest Community Hospital, Arlington Heights

60153

Cardinal Bernardin Cancer Center at Loyola University Medical Center, Maywood

60426

Ingalls Cancer Care Center at Ingalls Memorial Hospital, Harvey

63110

Siteman Cancer Center at Barnes-Jewish Hospital, St Louis

63703

Cancer Institute of Cape Girardeau, Cape Girardeau

65802

CCOP - Cancer Research for the Ozarks, Springfield

65804

St. John's Regional Health Center, Springfield

65807

Hulston Cancer Center at Cox Medical Center South, Springfield

68114

Methodist Cancer Center at Methodist Hospital - Omaha, Omaha

70112

Tulane Cancer Center, New Orleans

70121

CCOP - Ochsner, New Orleans

74136

Natalie Warren Bryant Cancer Center at St. Francis Hospital, Tulsa

83706

Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center, Boise

84106

Utah Cancer Specialists at UCS Cancer Center, Salt Lake City

84107

Cottonwood Hospital Medical Center, Murray

84143

LDS Hospital, Salt Lake City

84403

McKay-Dee Hospital Center, Ogden

84603

Utah Valley Regional Medical Center - Provo, Provo

84770

Dixie Regional Medical Center, St. George

85013

Foundation for Cancer Research and Education, Phoenix

87106

University of New Mexico Cancer Research and Treatment Center, Albuquerque

89106

CCOP - Southern Nevada Cancer Research Foundation, Las Vegas

91505

Providence Saint Joseph Medical Center - Burbank, Burbank

91767

Pomona Valley Hospital Medical Center, Pomona

92354

Loma Linda University Cancer Institute at Loma Linda University Medical Center, Loma Linda

93720

Saint Agnes Medical Center, Fresno

95815

Radiological Associates of Sacramento Medical Group, Inc., Sacramento

97030

Legacy Mount Hood Medical Center, Glesham

97062

Legacy Meridian Park Hospital, Tualatin

97210

Comprehensive Cancer Center at Legacy Good Samaritan Hospital & Medical Center, Portland

97213

Providence Cancer Center at Providence Portland Medical Center, Portland

97222

Providence Milwaukie Hospital, Milwaukie

97225

CCOP - Columbia River Oncology Program, Portland

Providence St. Vincent Medical Center, Portland

97227

Institute of Oncology at Vilnius University, Portland

98101

CCOP - Virginia Mason Research Center, Seattle

98668

Southwest Washington Medical Center Cancer Center, Vancouver

98902

North Star Lodge Cancer Center, Yakima

91346-9600

Providence Holy Cross Cancer Center, Mission Hills

06520-8032

Yale Comprehensive Cancer Center at Yale University School of Medicine, New Haven

60611-3013

Robert H. Lurie Comprehensive Cancer Center at Northwestern University, Chicago

60637-1470

University of Chicago Cancer Research Center, Chicago

03301

Dartmouth - Hitchcock Concord, Concord

03756

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center, Lebanon

08103

Cancer Institute of New Jersey at the Cooper University Hospital, Camden

Cooper Cancer Institute, Camden

08818

John F. Kennedy Medical Center, Edison

07740

Monmouth Medical Center, Long Branch

08755

Community Medical Center, Toms River

17033-0850

Penn State Cancer Institute at Milton S. Hershey Medical Center, Hershey

05201

Green Mountain Oncology Group, Bennington

05401

Fletcher Allen Health Care - University Health Center Campus, Burlington

05701

Community Cancer Center at Rutland Regional Medical Center, Rutland

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

Radiation Therapy Oncology Group

NETWORK

NCT00099125 - Radiation Therapy, Temozolomide, and Irinotecan in Treating Patients With Newly Diagnosed Glioblastoma Multiforme | Biotech Hunter | Biotech Hunter