Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases

PHASE2CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

October 31, 2004

Primary Completion Date

September 30, 2006

Conditions

Central Nervous System MetastasesHER2-positive Breast CancerMale Breast CancerRecurrent Breast CancerStage IV Breast CancerTumors Metastatic to Brain

Interventions

DRUG

lapatinib ditosylate

Given orally

OTHER

laboratory biomarker analysis

Correlative studies

PROCEDURE

quality-of-life assessment

Ancillary studies

OTHER

questionnaire administration

Ancillary studies

Trial Locations (1)

Dana-Farber Cancer Institute, Boston

All Listed Sponsors

lead

National Cancer Institute (NCI)

NIH

NCT00098605 - Lapatinib in Treating Brain Metastases in Patients With Stage IV Breast Cancer and Brain Metastases | Biotech Hunter | Biotech Hunter